Metabolic Health
Peptides commonly researched in the context of insulin sensitivity, glycemic control, lipids, and mitochondrial function.
Metabolic conditions like type 2 diabetes or PCOS need diagnosis and monitoring by a clinician.
Semaglutide
Strong Human EvidenceA GLP-1 receptor agonist FDA-approved for type 2 diabetes (Ozempic) and chronic weight management (Wegovy).
Tirzepatide
Strong Human EvidenceA dual GIP/GLP-1 receptor agonist FDA-approved for type 2 diabetes (Mounjaro) and chronic weight management (Zepbound).
Retatrutide
Moderate Human EvidenceAn investigational triple GLP-1 / GIP / glucagon receptor agonist showing the largest weight-loss effects yet seen in mid-stage trials.
NAD+
Limited Human EvidenceA central coenzyme in energy metabolism that has been studied as a supplement and IV therapy for aging, fatigue, and metabolic health.
MOTS-c
ExperimentalA mitochondrial-encoded peptide studied for its role in metabolism, exercise capacity, and mitochondrial signaling.
Tesamorelin
Strong Human EvidenceA long-acting GHRH analog FDA-approved as Egrifta for HIV-associated visceral fat accumulation.
5-Amino-1MQ
Animal / LabA small-molecule NNMT inhibitor studied in obese mice for reducing fat mass and raising cellular NAD+ and SAM levels.
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